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Long-term effects of guar gum in subjects with non-insulin-dependent diabetes mellitus |
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Per-Henrik Groop, Antti Aro, Svante Stenman, and Lief Groop
Abstract
The effects of 15g guar gum/d on glycemic control, lipids, and insulin secretion
were studied in 15 (8 male, 7 female) diet-treated subjects with non-insulin-dependant
diabetes mellitus for 48 wk. Mean age (+2y (range 45-70), body mass index (in kg/m2) 28.6 +- 0.9 (range 21.6 +- 39.2), and duration of diabetes 6 +- 1 yr (range 2-14 y).
Guar gum was preceded and followed by 8-wk placebo periods. Guar gum improved long-term
glycemic control, postprandial glucose tolerance and lipid concentrations. The
C-peptide response to a test meal increase by time during guar gum treatment, whereas
the insulin response remained unchanged. This indicates that insulin secretion is enhanced by guar gum as reflected by increased C-peptide. A decreased molar ratio of
insulin to C-peptide suggests that guar gum may increase hepatic insulin extraction.
In conclusion, guar gum has favorable long-term effects on glycemic control and lipid
concentrations.
THE LOWERING OF SERUM
CHOLESTEROL WITH A Abstract High levels of serum cholesterol have been linked with coronary heart disease(CHD) for over 30 years. Early interventions included the prescription of drugs that inhibited the production of cholesterol and a reduction in the dietary intake of cholesterol. In recent years prescription therapy has advanced in the fight against CHD. But this does not fully address the associated dangers. These include dangerous but manageable side effects, drug interactions, excessive costs and insurance claims. There is accumulating evidence suggesting that dietary fiber can reduce serum cholesterol. The current study was designed to investigate the serum cholesterol lowering effect of a patented dietary fiber supplement Subjects (n--66) were taken from a random blinded pool of patients currently at risk for CHD. Patients were monitored for total cholesterol (TC). low density lipoprotein (LDL), high density lipoprotein (HDL), triglyceride (TG) and cardiac risk (HDL:LDL). Fasting blood samples were obtained at the beginning of the study and then monthly for three months. The results indicate the highest significant reductions in serum TC (-14.9%) and serum LDL (-17.9%) were achieved within the first 60 days of using the fiber supplement. HDL increased (+30.1%) Significantly while TG decreased (-30.7%). These statistics show overall highly Significant results in (TIC), (HDL), (LDL), (TG). The most notable of these results is the highly significant reduction of cardiovascular risk (-36%) in the HDL: LDL risk ratio. TC reduction was seen as high as (+45%) with LDL decreases as low as (-59%) and HDL increase as high as (+48%). This variability is consistent with blood sampling and lack of diet and exercise restrictions. In conclusion, the use of a natural dietary fiber supplement, as part of an overall diet, proved highly successful in lowering risk factors associated with Coronary Heart Disease (CHD). The Basis for Using Nutritional Supplemetation BIOSLife 2 is a matrix of soluble fibers, B vitamins, minerals and chromium polynicotinate and has two patents for the method and composition of reducing serum cholesterol and a patent for leveling blood sugars. Nature Force is a whole food antioxidant containing cruciferous vegetables as well as European wine grapes and green tea extracts reduced to tablet form.
Benefits of taking BiosLife 2 and
Nature Force together:
How the supplements work:
BiosLife 2
Bioslife 2 -Weight Management
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